Comparison of amplicor and GeneXpert MTB/RIF tests for diagnosis of tuberculous meningitis.

نویسندگان

  • Vinod B Patel
  • Cathy Connolly
  • Ravesh Singh
  • Laura Lenders
  • Brian Matinyenya
  • Grant Theron
  • Thumbi Ndung'u
  • Keertan Dheda
چکیده

There are no data about the comparative accuracy of commercially available nucleic acid amplification tests (GeneXpert MTB/RIF and Roche Amplicor) for the diagnosis of tuberculous meningitis (TBM). A total of 148 patients with suspected TBM were evaluated, and cultures served as the reference standard. The sensitivities and specificities (95% confidence interval [CI]) for the Amplicor and Xpert MTB/RIF tests were similar: 46 (31-60) versus 50 (33-67) and 99 (93-100) and 94 (84-99), respectively.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 52 10  شماره 

صفحات  -

تاریخ انتشار 2014